Our team’s scientific publications

Published research.

Kunisaki J, et al. (medRxiv 2024)

Sperm from infertile, oligozoospermic men have elevated mutation
rates

Lu X, Luo Y, Nie X, et al. (Nat Commun 2023)

Single-cell Multi-omics Analysis of Human Testicular Germ Cell Tumor Reveals its Molecular Features and Microenvironment

Wamaitha SE, Nie X, et al. (Dev Cell, 2023)

Single-cell analysis of the developing human ovary defines distinct insights into ovarian somatic and germline progenitors

Nie X, et al. (Dev Cell. 2022)

Single-cell analysis of human testis aging and correlation with elevated body mass index

Hickey GJ, et al. (Elife. 2022)

Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos

Chen H, et al. (Cell Rep. 2021)

Dissecting mammalian spermatogenesis using spatial transcriptomics

Mahyari E, Guo J, et al. (Am J Hum Genet. 2021)

Comparative single-cell analysis of biopsies clarifies pathogenic mechanisms in Klinefelter syndrome

Guo J, et al. (Cell Stem Cell. 2021)

Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment

Guo B, et al. (Cancer Res. 2020)

Chromatin Looping Shapes KLF5-Dependent Transcriptional Programs in Human Epithelial Cancers

Guo B, et al. (Cancer Cell. 2020)

MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate

Guo B, et al. (Mol Cell Bio. 2020)

MAML1-Dependent Notch-Responsive Genes Exhibit Differing Cofactor Requirements for Transcriptional Activation

Guo J, Nie X, et al. (Cell Stem Cell. 2020)

The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty

Kircher D, et al. (Mol Cancer Res. 2019)

AKT1(E17K) Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis

Guo J, et al. (Cell Res. 2018)

The adult human testis transcriptional cell atlas